Scientists Grow “Synthetic” Mouse Embryo – With Brain and Beating Heart – From Stem Cells

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Scientists Grow “Synthetic” Mouse Embryo – With Brain and Beating Heart – From Stem Cells
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Scientists have created model mouse embryos from stem cells that have beating hearts, as well as the foundations for a brain and all of the other organs in the mouse body. Stem cells are the body's master cells, which can develop into almost any cell type in the body. The work was done by researcher

Natural and synthetic embryos side by side with heart and head folds stained in color. Credit: Courtesy of M. Zernicka-Goetz

Natural and synthetic embryos side by side show comparable brain and heart formation. Credit: Amadei and Handford “Our mouse embryo model not only develops a brain, but also a beating heart, all the components that go on to make up the body,” she explains. “It’s just unbelievable that we’ve gotten this far. This has been the dream of our community for years, and the major focus of our work for a decade, and finally we’ve done it.”

Over the past decade, Zernicka-Goetz’s team has been investigating these earliest stages of pregnancy to understand why some pregnancies fail and some succeed.

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