Gut microbiota and voluntary alcohol consumption - Translational Psychiatry

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Gut microbiota and voluntary alcohol consumption - Translational Psychiatry
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New insights into the influence of gutmicrobiota on alcoholconsumption

]. The first period of alcohol consumption began on the second day of fecal transplant. Rats were presented with two identical bottles in their home cages, one containing alcohol and another containing water. This paradigm involved three 1-h access sessions during the dark cycle, with the first session initiated at lights out and each subsequent period of access separated by 2-h of alcohol deprivation.

In the first step, operational taxonomic units were used for a more qualitative analysis approach of the samples . These data were analyzed with the QIIME 2 platform. Alpha diversity was measured using Evenness and additionally the Shannon’s diversity index . Beta diversity was measured based on Jaccard distance and the principal coordinates analysis plots were generated using Emperor for this Beta diversity metric.

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