Can some antihistamines wake some people up?

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Can some antihistamines wake some people up?
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Pharmacologists have known for decades that some people react differently to the...

Benadryl is shown Monday, March 6, 2000, in Philadelphia. Over-the-counter remedies like Benadryl, which is used by millions of hay fever sufferers, may impair driving more than alcohol, a new study indicates. The antihistamine found in Benadryl and many other over-the-counter allergy drugs had a greater impact than alcohol on participants' driving 'coherence,' or ability to match the speed of a vehicle they were following, according to the University of Iowa study.

Pharmacologists have known for decades that some people react differently to DPH. Instead of becoming drowsy, they may become agitated or anxious. One hypothesis is that these individuals metabolize DPH very rapidly to a stimulant compound . We wish the Food and Drug Administration required some information about this reaction on the “PM” pain reliever packaging.

Q: I’ve been taking the antidepressant bupropion for some time, and I’ve had multiple side effects. The worst was seizures caused by the medication. I fell on the ground, hit my head and lost consciousness. There is a seizure warning in the official prescribing information, which could make it challenging to find a lawyer who would be willing to take such a case. Your physician should have warned you about this potential risk.

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