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UC San Francisco researchers discovered a relationship between diets rich in vitamins and low in added sugars and a younger biological age at the cellular level, as determined by an “epigenetic clock” test. While high sugar intake was linked to accelerated biological aging, adherence to nutrient-rich diets, particularly the Mediterranean diet, was associated with significantly lower epigenetic age, demonstrating the negative impact of sugar on cellular longevity.
“The diets we examined align with existing recommendations for preventing disease and promoting health, and they highlight the potency of antioxidant and anti-inflammatory nutrients in particular,” said Dorothy Chiu, PhD, a postdoctoral scholar at the UCSF Osher Center for Integrative Health and first author of the study, which appears July 29 in.
“We knew that high levels of added sugars are linked to worsened metabolic health and early disease, possibly more than any other dietary factor,” Epel said. “Now we know that accelerated epigenetic aging is underlying this relationship, and this is likely one of many ways that excessive sugar intake limits healthy longevity.”
Finally, they scored the women’s diets against a measure they created called the “Epigenetic Nutrient Index ”, which is based on nutrients that have been linked to anti-oxidative or anti-inflammatory processes andmaintenance and repair. These include Vitamins A, C, B12, and E, folate, selenium, magnesium, dietary fiber, and isoflavones.
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