Your Good Health: Recognizing and diagnosing cold agglutinin disease

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Your Good Health: Recognizing and diagnosing cold agglutinin disease
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What are the symptoms for cold agglutinin disease, and how is it diagnosed?

Cold agglutinin disease is a specific type of anemia where antibodies attack and destroy a person’s own red blood cells. Unlike the usual type of autoimmune hemolytic anemia, the antibodies are only active below a person’s normal temperature, which is where the “cold” comes in. Thus, the red blood cells are destroyed in cool areas, such as the skin.

Diagnosis is usually made by an expert , as this is not a common disease, and many regular doctors like me are not very familiar with it. Specialized blood testing confirms the diagnosis, but the hard part is thinking about the condition in the first place. Is this something I should be concerned about? Are my coaster days coming to an end, or should I just avoid those coasters that feature inversions? I always try to get the front row if possible, since there is less of a chance of feeling head pressure from the g-forces. The steep drops don’t seem to affect me like the inversions do. Thank you for your response.A “greyout” is when the vision dims in light and color.

In people with a positive family history, screening begins at age 40 or 10 years before the earliest first-degree family member was diagnosed — whichever is earlier. The expert recommendation on screening intervals is every five to 10 years; personally, I prefer every five years in a person with positive family history.

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