Up to 20% of older people will have some kind of brittle nail condition
Dear Dr. Roach: I have a serious problem with my fingernails splitting and coming off at the edges. I have tried biotin and keratin for almost a year without results. I am an 89-year-old man who takes ibrutinib, Valtrex, allopurinol, cetirizine, and recently Eliquis and metoprolol succinate. Is there a solution for this sore, uncomfortable situation?Oncholysis is when the nail separates from the nail bed, while onychorrhexis is the splitting of the nails.
Biotin is a good choice to try, even though it’s only effective in about 25% of people with this condition, because it is safe and inexpensive. It does interfere with laboratory tests for hormones, especially the thyroid hormone, making test results seem abnormal when everything is OK. There are prescription nail lacquers that might be helpful if your oncologist has no alternative to ibrutinib.
In some people, many diabetes drugs can cause weight gain, such as insulin and those that increase insulin in the body like glyburide, glipizide and sitagliptin. Oral contraceptives that contain progestins can cause weight gain; this means all combination birth control pills and “minipills.”
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