Jardiance works by forcing your body to excrete glucose through the kidney, so bladder infections are possible. Increased urination is also very common.
Dear Dr. Roach: I am a 64-year-old man, and my A1C level has been averaging around 7.4% for a number of years. I was diagnosed diabetic at age 54. My doctor has been trying several combinations of drugs over the last couple years to get my A1C below 7%.
My general question is: With these three drugs, is there any way to tell which one is helping the most versus the least? If Jardiance is only helping 25% and the other two are helping 75%, then I would discontinue Jardiance and figure out another way to lower my A1C. Or I would only take metformin and Rybelsus and see what happens with my next A1C.
It is expected to lower the A1C level by about 0.5-0.7 percentage points; however, it has been shown to reduce heart disease risk in people with known blockages in their hearts and also protects the kidneys in people with diabetic kidney disease. It helps with weight loss as well. Based on the averages in the overall population with diabetes, Jardiance is likely to have the least effect on your A1C out of the three medicines that you are taking. My guess would be that 85% of your benefit is coming from Rybelsus and metformin. However, Jardiance could be helping your heart and kidneys more than expected, based on the predicted A1C change.
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