Although isotretoin can cause severe damage to the developing fetus if taken during pregnancy, a study showed that any effect on fertility was gone by 18 months after treatment.
Dear Dr. Roach: My daughter is in her 30s and has been experiencing infertility for several years. She and her husband have been tested, and the issue is her egg quality. She has had several rounds of in vitro fertilization with no success.
Now, years later, her fertility doctor says she has eggs, but they are of poor quality. What is your medical opinion on this medication affecting fertility? I read that Accutane was banned in 2009.Isotretoin is the most effective treatment for acne, but it has potential for serious side effects and can only be given after a thorough review of its risks.
Great care needs to be taken to prevent pregnancy with repeatedly negative pregnancy tests before starting therapy, as well as two forms of birth control in any person who could get pregnant . There is a high likelihood that a baby who is exposed to isotretoin will have severe damage or be stillborn. If a pregnancy occurs while on isotretoin, the drug must immediately be stopped, and the person needs to be referred to an expert in reproductive toxicity.
I wish your daughter the best of luck. I have had several patients give up after several rounds of IVF, only to conceive a healthy baby naturally.
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