What we know about COVID-19 variant Delta's newest offspring

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What we know about COVID-19 variant Delta's newest offspring
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The two Delta sub\u002Dlineages, dubbed AY.25 and AY.27, have been detected in every province except Prince Edward Island

The new variants seem to be increasing in frequency, Shapiro said. What’s not clear is what it means, if anything, for the biology of COVID-19. “If the infections are more severe, if they’re more likely to be causing breakthrough infections, we have no idea.”

However, “when you see it in separate jurisdictions, it does become increasing evidence that there is a real transmission advantage.” , because they’re significantly different from the original strain, increasing how quickly the virus spreads or causing more severe disease. Sub-lineages are more like twigs.Article content

It’s not clear what may make the new offshoots marginally more transmissible. AY.27 has changes in the spike protein the virus uses to enter human cells. The same mutation is also present in AY.4.2, the variant dubbed “Delta plus” that has been expanding across the United Kingdom.

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