Using cannabis while pregnant can affect placenta, stress, anxiety, development in children: study

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Using cannabis while pregnant can affect placenta, stress, anxiety, development in children: study
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Cannabis use during pregnancy has become increasingly common over the past two decades, but a study published Monday suggests that those children showed higher levels of cortisol, anxiety, aggression, and hyperactivity.

TORONTO -- Cannabis use during pregnancy has become increasingly common over the past two decades, but a study published Monday suggests that those children showed higher levels of a stress hormone, and greater anxiety, aggression, and hyperactivity.

“Pregnant women are being bombarded with misinformation that cannabis is of no risk, while the reality is that cannabis is more potent today than it was even a few years ago. Our findings indicate that using it during pregnancy can have long-term impact on children,” said Yasmin Hurd, Director of the Addiction Institute at Mount Sinai, and senior author of the paper, in a statement.

Researchers measured hair hormone levels, heart rate variability at rest and during auditory startle -- a test of an unconditional reflex caused by an unexpected loud sound -- of the children and looked at their neurobehavioral traits as measured on the Behavioral Assessment System for Children survey.

The placenta of some of the children with behavioural assessments were processed for RNA sequencing, with scientists finding that cannabis use during pregnancy was associated with lower expression of immune-activating genes, including proinflammatory cytokines and immune cell–type markers which help protect against pathogens.

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