Uncovering how the body ages is leading to drugs to reverse it

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Uncovering how the body ages is leading to drugs to reverse it
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Neanderthals' ear infections could have proved lethal

startup in California called Ambrosia began offering its customers transfusions of blood from the young. At $8,000 per litre, it was a service for the wealthy who believed that young blood could slow down or reverse the ageing process, thereby reducing their chances of developing cancers, Alzheimer’s disease and heart disease.

Earlier this year America’s Food and Drug Administration cautioned potential customers that there was no proven scientific benefit to receiving such blood. In response, Ambrosia shut down its clinics. But ill-fated startups aside, there is a kernel of truth to the idea that young blood can be rejuvenating.

The latest findings have been welcomed, albeit cautiously. Scientists at the American National Institute on Ageing say the latest work may show a way forward in a field that currently seems stuck. But they think it is too early to advance the research into human trials. The concern is that the drugs being used have not previously been tested together in people. Dr Conboy points out, however, that prescribing approved drugs in multiple combinations is a standard procedure in medicine.

Entrepreneurs in Silicon Valley might have jumped the gun in selling the rejuvenating effects of parabiosis to their clients. Nevertheless, this vampire-like concept is not gone yet—and could still rise up from the dead someday soon.section of the print edition under the headline

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