British researchers declare 59-year-old man free of Covid-19 after 411 days of persistent infection cured by cocktail of drugs
The man, who has a weakened immune system due to a kidney transplant, caught Covid in December 2020 and continued to test positive until January this year.
These patients can test positive for months or even years with the infection "rumbling along the whole time," Luke Snell said on Friday, a physician specialising in infectious diseases at Guy's and St Thomas' NHS Foundation Trust. To discover whether he had contracted Covid numerous times or if it was one persistent infection, the researchers used a rapid genetic analysis with nanopore sequencing technology.
Like most other antibody treatments, the treatment is no longer widely used because it is ineffective against newer variants such as Omicron. The researchers used several such treatments to try to save a seriously ill 60-year-old man in August this year who had been infected since April.So the team crushed up two antiviral treatments not previously used together — Paxlovid and remdesivir — and administered them to the unconscious patient via a nasal tube, according to a non-peer-reviewed preprint study on the website ResearchSquare.
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