The aim is a broader type of immune response than can be achieved just by injecting into the muscles of the upper arm, including a more potent T cell response,…
The vaccine is part of a second generation of COVID-19 vaccines and one of two Canadian-made formulas that hope to offer a more robust, and more stable immune response. On Tuesday, Quebec-based Medicago Inc. is due to report results from its Phase 3 trial of its plant-based vaccine that involved some 24,000 people, the last step of testing before possible approval.
But with SARS-CoV-2 set to linger for months, perhaps years, and more booster doses likely to follow, it’s still important to test new vaccines that work in different ways, Smaill said. The vaccine uses strains of a weakened adenovirus, a family of viruses that cause the common cold. Two are being tested on 30 healthy volunteers — a vaccine using a human adenovirus, the other a chimpanzee adenovirus.
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