A genetic mutation linked to skin cancer in humans caused these leopard geckos to develop the quirky 'Lemon Frost' color pattern.
cells that produce melaninbut many other animals have more than one type of color cell, producing a variety of pigments which result in numerous skin and scale colors. For example, cephalopods like cuttlefish and octopus have at least
Model organisms are used to study human biology and disease because of the range of information and experimental possibilities they provide. “There’s a lot of experiments that we can do on model organisms that, you know, obviously, you can’t do on people,” says Ceol. “You can do these experiments where you give [animals] a cancer, and then look to treat it, or look to study the process by which the cancer arises, or by which it spreads.
But until relatively recently, scientists haven’t had the tools to study the genetics of non-model organisms. Identifying genes in previously unstudied animals required years of genome mapping . Now though, new methods have allowed scientists to use other, well-mapped genomes as the jumping off point to learn more about less understood organisms like leopard geckos.
For now, Ceol says, he’ll be sticking to zebrafish. “I’m not sure that I would go out and adopt [leopard geckos] as a model myself.”
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