The Science Behind Dog DNA Tests

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The Science Behind Dog DNA Tests
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The popular mail-in kits have arrived thanks to a sweeping research project that maps the canine genome, similar to efforts with human genetics.

and made breed detection kits more affordable for consumers. Multiple companies now offer them for about $100, as well as premium kits that test for drug sensitivities or mutations such as Acra Mutilation Syndrome, in which a dog doesn’t feel pain and is at risk for hurting themselves.The test process begins with an at-home kit that includes two small cytology brushes, which are used to collect cheek cells from inside the dog’s mouth.

At Wisdom Panel, laboratory technicians place the brush into a solution to extract the DNA. The DNA is then separated into single strands and snipped to isolate SNPs, orThese small segments are labeled with fluorescent tags and put onto a, a tool that resembles a grid with dozens of small wells. In each well, the segments attach to DNA samples called probes, which contain trait and breed information from the broader dog genome.

All in all, Wisdom Panel can read approximately 100,000 different SNPs at once, Foran says. Within two weeks, the consumer receives a report detailing their dog or cat’s breed as well as the notable genetic traits related to ear type, face shape and coat variations.Sofia’s DNA was compared with a database of 20,000 purebred dogs, and her test revealed that she is indeed mostly a chihuahua — 71 percent, to be exact.

In addition to identifying the presence of breed types as low as 1 percent, the test also identifies the genes that give dogs their appearance. As for coat colors, the test looks for variants in chocolate, dominant black, recessive black, fawn, recessive red, and widow’s peak . The genetic coat variations help explain why the rescue thought Sofia was a dachshund. She has two copies of a chocolate gene (

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