Since the start of the COVID-19 pandemic, doctors have been trying to figure out why some people with coronavirus develop severe inflammation.
Apr. 7, 2022 -- Since the start of the COVID-19 pandemic, doctors have been trying to figure out why some people with coronavirus develop severe inflammation, which can lead to respiratory distress and damage organs.and conducted by researchers at Boston Children’s Hospital and Massachusetts General Hospital provides a possible answer.
Lieberman told CNN the study helps explain why older people and people with underlying health conditions, such as diabetes and obesity, are more likely to become severely ill with COVID, since those conditions already have some inflammation. The research team examined blood samples from COVID patients at Massachusetts General Hospital and compared them with blood samples from healthy people and patients with other respiratory illnesses. They also looked at lung autopsy tissue from COVID fatalities.About 6% of blood monocytes found in infected COVID patients died “an inflammatory death,” as did about a quarter of macrophages from the lung tissue, the Boston Children’s Hospital news release said.
Researchers noticed that people with COVID had a higher number of monocytes carrying a receptor called CD16, Boston Children’s Hospital said. Antibodies, which are naturally produced by the body to fight off a virus, attach to the CD16 receptors.
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