Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis - Nature

Nature research paper: Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis

This work was supported by the National Institutes of Health and the Eberly Family Distinguished Chair in Science . S.J.B. is an investigator of the Howard Hughes Medical Institute. This research used resources of the Advanced Photon Source, a US Department of Energy Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under contract no. DE-AC02-06CH11357.

This research also used the resources of the Berkeley Center for Structural Biology supported in part by the Howard Hughes Medical Institute. The Advanced Light Source is a Department of Energy Office of Science User Facility under contract no. DE-AC02-05CH11231. The ALS-ENABLE beamlines are supported in part by the NIH, National Institute of General Medical Sciences, grant P30 GM124169. E.K.S. and C.A.T. thank M. S. Lichstrahl for providing a synthetic intermediate, and I. P. Mortimer and J.

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