Environmental factors like prolonged stress, chronic inflammation and toxic exposure could play a key role in triggering Parkinson's disease, even in people without genetic risk.
RELATED: More than 100,000 Canadians currently live with Parkinson’s disease. Research from McGill University is assessing a new drug compound that could help treat Parkinson's disease in young patients. Dr. Kalle Gehring joined our Brenden Purdy with more – Nov 18, 2024The researchers discovered that an immune response plays a crucial role in forming toxic protein clumps, known as Lewy bodies, within brain cells, contributing to the disease’s progression.
“This marks a significant step forward to understanding key aspects of Parkinson’s and other neurological diseases,” he said in aParkinson’s disease is a progressive neurological disorder that affects movement, often causing tremors, stiffness and difficulty with balance and coordination.
This suggests factors that trigger the immune system, such as chronic inflammation, exposure to toxins or prolonged stress may not only correlate with Parkinson’s, as previous research has found, but drive its development, the researchers said. “Inflammation is under-studied and not very well understood in terms of the role it plays with neurological conditions such as Parkinson’s,” she said.
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