Spinal Cord Stimulation Restores Post-Stroke Arm, Hand Function

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Spinal Cord Stimulation Restores Post-Stroke Arm, Hand Function
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For the first time, researchers have used electrical stimulation of the cervical spinal cord to immediately restore arm and hand movement in two patients with chronic moderate-to-severe upper limb paresis.

"Stroke is the largest cause of paralysis in the world," with nearly three quarters of patients with stroke experiencing lasting deficits in motor control of their arm and hand, co-senior study author Marco Capogrosso, PhD, assistant professor of neurological surgery at the University of Pittsburgh, Pittsburgh, Pennsylvania, said during a press briefing.

In this"first-in-human" study, the investigators percutaneously implanted two linear leads in the dorsolateral epidural space targeting neural circuits that control arm and hand muscles in two patients. In both patients, continuous stimulation of the targeted neural circuits led to significant and immediate improvement in arm and hand strength and dexterity. This enabled the patients to perform movements that they couldn't perform without spinal cord stimulation.

The researchers noted, however, that further studies in larger cohorts will be required to validate the safety and efficacy of this approach.

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