New University of Toronto research found some coffee drinkers may need to start putting up boundaries with caffeine or face an increased risk of kidney dysfunction.
, said about half of the population has a genetic variant that means their body is slow at metabolizing caffeine. Coffee enthusiasts who drink more than three cups a day – and are also slow metabolizers – are at risk of kidney dysfunction, the study found.
The study found slow metabolizers who drink more than three cups of coffee per day are nearly three times more likely to, which can impede on the organ’s ability to filter waste from the blood. Unmanaged, it can lead to long-term damage, such as kidney failure. Much of her work dove into measuring that extra stress. Caffeine can become a toxin in the human body when it’s in a high concentration, Mahdavi explained. The key difference is slow metabolizers break down those toxins slower, which increases the likelihood of adverse effects.
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