By switching genes on and off, cigarettes have a long-lasting effect on immunity, and appear to shape your immune system just as much as aging.
It’s 2024—we know that cigarettes are bad for you. But scientists are still uncovering new and troubling ways that smoking changes you from the inside out. Today in Nature, a new study from the Institut Pasteur in Paris reports that smoking has a lingering effect on the immune system that persists long after taking your last drag. The health of your immune system is defined by how well it responds to things.
Seemingly everything from wildfire smoke to your parents’ trauma has been linked to epigenetic changes—physical manipulations of the DNA molecule that switch genes on or off. Sure enough, the long-term effect of smoking on the immune response also appears to be linked to epigenetics. Duffy admits that interpreting these effects can get weird.
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