One of the first carefully done studies of the antiviral drug remdesivir shows it did not help people recover faster from coronavirus infections. But the study, conducted in China, may have been too small to show clearly whether the drug helps.
The findings of the Chinese study conflict with other hints of the drug’s efficacy coming from other trials – two of them also on Wednesday. One study was from the company that makes the drug and a third study from the National Institutes of Health is expected later on Wednesday.
The study conducted in China was stopped early because there weren’t enough patients, but it indicated that the drug did not work as hoped, the team reported in the Lancet medical journal on Wednesday. Some details of this study were posted last week on the World Health Organization’s website, then removed.
The Lancet study was a randomized, placebo controlled study – meaning that patients were randomly given the drug or a dummy treatment and the patients and doctors did not know who was getting what. “Unfortunately, our trial found that while safe and adequately tolerated, remdesivir did not provide significant benefits over placebo,” Bin Cao, the researcher who led the study, said in a statement.
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