The deadly brain cancer is no longer a mystery.
Glioblastoma is one of the most dangerous cancer types affecting the human brain and spinal cord. Overlose their lives because of nervous system cancer annually, and in most of these cases, the leading cause of death is glioblastoma.
Its tumors spread fast and induce highly painful seizures and headaches. What’s worse is that there is no known 100 percent effective cure for this disease. US president Joe Biden’s eldest son Beau Biden and late American actor Robert Forster were also among the many victims of glioblastoma.However, now a team of researchers at Cold Spring Harbor Laboratory in New York has figured out why
in nature. They have also proposed a mechanism that could be employed to control and cure this deadly cancer in humans.According to the researchers, by its occult nature, glioblastoma is deadly since it is not usually detected early. It tends to grow quickly and disrupt brain functions. When it all of a sudden appears, theHowever, its many different cancer cells take on numerous forms.
During their study, the authors discovered that a protein called BRD8, which packages our genome when becomes highly active, causes glioblastoma., “You can think of BRD8 as protein machinery that packages our genome, unfortunately, sometimes in a bad way. Too much of it makes glioblastoma—the most common adult cancer that starts in the brain—thrive. We discovered that we can shut down glioblastoma by turning off BRD8.
Their study suggests that by targeting and shutting down BRD8, the unmutated P53 genes in patients can be reactivated. These tumor-suppressing genes will then stop tumor growth and eventuallyThe inverse relationship between BRD8 and P53.
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