Sanofi discontinued the ranitidine formulation of Zantac, and the new formulation, Zantac 360, is made with a different active ingredient.
The French pharmaceutical company Sanofi says it has reached an agreement to resolve 4,000 cases in the U.S., in which plaintiffs are linking the discontinued heartburn drug Zantac — and its active ingredient ranitidine — to cancer. Sanofi has long denied these claims.
Sanofi adds that medical experts “have found the allegations of the plaintiffs to be without merit.” And in 2022, in a lawsuit brought by other plaintiffs in another Zantac case, a U.S. federal court judge ruled “the plaintiffs had no reliable evidence.”Peter Pitts, the former associate commissioner of the FDA, says these types of lawsuits are concerning for the industry.
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