Routine periodic fasting associated with lower hospitalization risk in patients with COVID-19 BMJNutrition Intermountain SARSCoV2 COVID19 Fasting KetogenicDiet SevereCOVID
By Dr. Priyom Bose, Ph.D.Aug 1 2022Reviewed by Aimee Molineux Scientists have worked extremely hard to understand the various aspects of the novel coronavirus, namely, severe acute respiratory syndrome coronavirus 2 , the causal agent of the ongoing coronavirus disease 2019 pandemic. Recently, they evaluated the impact of intermittent fasting on COVID-19 disease severity. This study is available in BMJ Nutrition, Prevention & Health.
Previous studies have reported that galectin-3 controls inflammation via proinflammatory actions, in response to acute infection. Therefore, galectin-3 has been associated with anti-inflammatory functions during acute infection. This protein lowers the risks of chronic metabolic disorders. Interestingly, scientists have detected an increased level of galectin-3 in patients with cardiac issues and diabetes.
About the study The main objective of the prospective observational cohort study was to evaluate whether periodic fasting is linked with severe COVID-19 symptoms. Researchers also studied if periodic fasting could predict the onset of SARS-CoV-2 infection. The authors reported that 1524 patients fasted periodically, i.e. fasted routinely for five years or more. Among them, 205 patients tested SARS-CoV-2 positive, and the rest of the patients tested negative. The study cohort considered in this study was before COVID-19 mass vaccination.
The authors believe that an elevated amount of linoleic acid that binds to the spike protein of SARS-CoV-2, reduces the number of infected cells or the SARS-CoV-2 virions in cells. This leads to a decrease in the COVID-19 infection severity. Similar benefits could be achieved by following ketogenic diets.
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