Australian researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.
and sophisticated statistical genomics to discover clinically relevant bacterial factors that influence infection outcomes."
University of Melbourne Professor Ben Howden, Director of the Microbiological Diagnostic Unit Public Health Laboratory at the Doherty Institute and co-senior author of the paper, said that this work represents a significant advancement inas it reshapes our strategies against complex health challenges like Golden staph infections.
"By revealing the genes responsible for antibiotic resistance in Golden staph, our GWAS is pointing the scientific community to clearer targets for the development of effective solutions to treat Golden staph bloodstream infections," said Professor Howden. "This knowledge has the potential to shape and enhance our ability to tackle these persistent infections. As bacterial genomes become increasingly available in the clinical routine, we inch closer to customized therapeutic strategies, where treatments will be tailored to the unique genetic makeup of the infecting strain, rather that treating everyone in the same way.
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