It is currently unclear where T cells in the brains of teleosts originate from. While viewing the central nervous system (CNS) as immune privileged has been widely accepted, previous studies suggest that T cells residing in the thymus but not in the spleen of the teleost play an essential role in communicating with the peripheral organs.
Research finds T cell subset significantly expands in spleen and brain after virus infection retrieved 27 March 2024 from https://medicalxpress.com/news/2024-03-cell-subset-significantly-spleen-brain.html
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