Sculpting the humanbody plan in a dish nature
gene expression dynamics in MG embedded axioloids. Live imaging of the spatiotemporal morphogenetic expression of thegene in a 201B7 Luc-derived axioloid embedded in MG from 72h to 120h of culture. BF video and HES7:Luciferase signal . Data shown is representative of at least three independent experiments. Scale bar is 200 µm.Effect of retinoid signaling on axioloid growth and morphology.
Scale bar is 200 µm.3D reconstruction of somites in axioloids and human CS9-11 embryos. 3D reconstruction of somites formed in 409B2-derived MG embedded axioloids treated retinol , retinal and retinoic acid ; and 3D reconstructions of somites in human embryos found in CS9 , CS10 and CS11 human embryos. Each somite-like structure is highlighted by a different color depending on its position along the antero-posterior axis.gene expression dynamics.
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