News & Views: An encouraging phase 1 trial underscores the need for more research into classic psychedelics for treatment of anorexia nervosa, to address the urgent need for effective treatments. StefanEhrlich3 tudresden_de ChariteBerlin
, ten participants with AN of 19.7) received one dose of psilocybin together with psychological support. The treatment was shown to be safe, well tolerated, and acceptable to patients.
Adverse effects were mild and mirrored typical psilocybin-associated symptoms such as transient headache, nausea and fatigue; no serious medical or psychiatric adverse events were reported. Shape concerns significantly decreased at the 1 month follow-up, and four patients had decreases in eating disorder scores at 3 months that qualified them for remission from eating disorder psychopathology.
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