Your gut microbiome is getting a tech upgrade
is the company that successfully developed the world’s first genetically engineered probiotic. Their bioengineered probiotic bacteria has been designed to increase the production of the chemical factories in your body that break down a toxic chemical byproduct of alcohol in your gut. In other words, they’ve invented a hangover cure — but you have to ingest it before or during drinking.
But hangovers aren’t exactly a disease. Synlogic is targeting phenylketonuruia, a rare genetic disorder that prevents patients from breaking down an amino acid called phenylalanine. They’re also developing cancer therapeutics that work without persisting or accumulating in the body. Synlogic believes that living medicines could be used as anti-cancer agents, activating your own body against cancer cells, and potentially improving the effectiveness of other immunomodulatory treatments.
Your entire body is full of microbes, and several companies are targeting diseases that affect other areas of your body, like your skin or your mouth.Your skin also harbors a vast microbiome. What you place on your skin - whether a decorative cosmetic, moisturizer, or medicine — certainly influences your skin microbes.is a pre-clinical stage microbiome company developing probiotics to treat skin diseases like eczema.
Like the study of the microbiome, the field of engineered probiotics is relatively new and regulations around it are still evolving. Companies may be reluctant to fully invest in new probiotics until regulations are in place that both protect consumers and encourage innovation. This above list is by no means comprehensive. The future of engineered probiotics is exciting and I believe their impact on human health will be widespread.
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