Stress affects fetus' ability to absorb iron, study finds SciReports
With our ML approach, we mimicked a real-life scenario to identify mother–fetus dyads affected by PS. Our results are consistent with findings in other clinical settings where electronic medical record mining identified patients at risk even without additional biophysical assessments, such as ECG
. Notably, adding biophysical characteristics improves ML model performance, thus emphasizing the potential of antepartum mother–child monitoring using taECG to improve the early detection of health abnormalities such as PS.Strengths of the FELICITy study are the prospective design preventing recall bias and the definition of criteria for a matching system to exclude possible confounders.
We chose not to include other potential effect modifiers on the causal pathway of the DAG such as inflammatory processes as they are difficult to define quantitatively and were not the focus of this study. However, future studies could further refine estimates ofThis study did not differentiate between arterial or venous origin of the analyzed cord blood samples. To our knowledge this issue has not been addressed in literature so far.
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