Research published Wednesday marked another advance in the push for animal-to-human transplants, which is being developed at UAB and several other hospitals around the country.
From side, Loren Brook Eichelberger, RN is measuring urine output of xenotransplantation patient, 2023.A genetically modified pig kidney transplanted into a brain-dead patient in Alabama earlier this year worked for seven days, according to research published Wednesday.
Kidney disease affects up to 15 percent of the adult population and is a common cause of death in the United States, according to the National Kidney Foundation. Transplantation is the gold-standard treatment, but organ shortages have created long waitlists. Many patients die before donor organs become available.
The study was conducted in February 2023 on a patient who had been declared brain dead and had a history of chronic kidney disease. The patient, who is not being named, is the third to undergo a procedure to have his kidneys removed and replaced by genetically modified pig organs at UAB. After the transplant, he was treated with standard immunosuppressant drugs.
On the same day that JAMA Surgery published the article about UAB”s kidney transplant, NYU’s Langone Medical Centerthat a transplanted pig kidney with just one edited gene was functioning well 32 days after it was transplanted into the body of a brain dead patient.
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