Pfizer says tweaked COVID-19 shots boost omicron protection
Pfizer announced Saturday that tweaking its COVID-19 vaccine to better target the Omicron variant is safe and works – just days before regulators debate whether to offer Americans updated booster shots this fall.
Now with Omicron’s even more transmissible relatives spreading widely, the Food and Drug Administration is considering ordering a recipe change for the vaccines made by both Pfizer and rival Moderna in hopes that modified boosters could better protect against another COVID-19 surge expected this fall and winter.
In a study of more than 1,200 middle-aged and older adults who’d already had three vaccine doses, Pfizer said both booster approaches spurred a substantial jump in Omicron-fighting antibodies. And importantly, preliminary lab studies show the tweaked shots also produce antibodies capable of fighting Omicron’s genetically distinct relatives named BA. 4 and BA. 5, although those levels weren’t nearly as high.
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