Northwestern performs first heart transplant in Illinois using ‘heart-in-a-box’ device

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Northwestern performs first heart transplant in Illinois using ‘heart-in-a-box’ device
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Surgeons took a heart that stopped beating inside a patient and successfully transplanted it with the help of a science fiction-like device

A donated heart is examined and perfused with blood while being prepared for transplant using the TransMedics Organ Care System Heart. Nicknamed “Heart in a Box,” this new technology resuscitates a stopped heart, keeping it pumping outside of the body until it can be transplanted into a waiting patient.

The heart in a box device, however, allows surgeons to use hearts from donors who suffer circulatory death, which is when the heart and respiratory system shut down. After the heart stops beating, surgeons have about 30 minutes to retrieve it and place it in the device. The device then resuscitates it and keeps it beating by pumping warm, oxygenated blood through it, until it can be transplanted into a donor.

Until now, patients usually could not be considered as potential donors unless they were brain dead, limiting the number of hearts available. The new technology allows surgeons to take hearts from patients who are not technically brain dead, but have no hope of recovery.

Because the device keeps the heart pumping, surgeons have more time to transplant it than with traditional methods. The device can keep the heart viable for eight or nine hours, compared with about four or five hours when a stopped heart is on ice before a transplant.

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