STOCKHOLM (AP) — Two scientists won the Nobel Prize in physiology or medicine on Monday for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that help control what the cells do and when they do
STOCKHOLM — Two scientists won the Nobel Prize in physiology or medicine on Monday for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that help control what the cells do and when they do it.
Ambros and Ruvkun were initially interested in genes that control the timing of different genetic developments, ensuring that cell types develop at the right time. “Their groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans,” according to the citation explaining the importance of their work.
“If we take the example of cancer, we’ll have a particular gene working overtime, it might be mutated and working in overdrive,” said Fletcher. She said scientists might one day be able to use microRNA to stop such effects. Miska said there is ongoing work on the role of microRNA in infectious diseases like hepatitis and that it might also be helpful in treating neurological diseases.
Going to pick up his award in December will be the third time he has been to a Nobel Prize ceremony in Stockholm after attending to watch his mentor Robert Horvitz receive the 2002 award and then his buddy Jack Szostak, who won in 2009.Ambros said he didn’t expect the award as he felt that the Nobel committee has already singled out RNA in the 2006 prize that went to his friends Andrew Fire and Craig Mello.
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