New syndrome in children thought to be linked to COVID-19 yields surprising test results

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New syndrome in children thought to be linked to COVID-19 yields surprising test results
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Of 21 suspected cases in children treated at Montreal’s Sainte-Justine Hospital, only four had antibodies to SARS-CoV-2, the virus that causes COVID-19

This translation has been automatically generated and has not been verified for accuracy.When frightening reports began to emerge in the spring of British and U.S. children falling severely ill with an inflammatory syndrome linked to COVID-19, Montreal’s Sainte-Justine Hospital was the first to report a cluster of similar cases in Canada.

The Sainte-Justine patients are only a small sample, but the results suggest MIS-C is perhaps rarer in Canada than it first appeared. MIS-C, which the Canadian Paediatric Society sometimes calls PIMS-TS, is generally marked by fever, intestinal distress, elevated inflammation levels on laboratory tests and the overlapping symptoms of toxic-shock syndrome and Kawasaki disease, a rare childhood illness that inflames the blood vessels, most dangerously in the heart.

But in Canada, no children are known to have died of MIS-C, and only a handful of those suspected of having it were in intensive care, pediatric hospitals and provincial health officials say. CHEO, formerly known as the Children’s Hospital of Eastern Ontario, is investigating more than 20 possible cases, all of them negative for an active infection, spokesman Paddy Moore said.

That has posed a problem in Canada, where blood tests for coronavirus antibodies are not routinely available, even though Health Canada has approved several.

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