The process of genome mining reveals a common category of naturally occurring compounds that have the potential as viable drug candidates. Researchers at the Max Planck Institute for Terrestrial Microbiology have discovered the biosynthesis of a rare compound called benzoxazolinate, which is found
Natural products containing benzoxazolinate, a structure with two rings, are excellent candidates for pharmaceutically valuable substances, such as antibiotics, anticancer drugs, or immunosuppressants. But how can their producers be identified? Credit: Max Planck Institute for Terrestrial Microbiology/Crames
By utilizing genomic research, scientists were able to uncover the previously unknown genes responsible for its formation. This breakthrough opens doors to the discovery of a multitude of new natural compounds with medical applications. In order to exploit new pharmaceutically valuable natural compounds, like antibiotics, tumor suppressants, or immunosuppressants, it is necessary to know the responsible genes, or more precisely, their biosynthetic gene clusters . BGCs are locally clustered groups of two or more genes that together encode the production of a certain set of enzymes – and thus the corresponding natural products produced by these enzymes.
Canada Latest News, Canada Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Animal Crossing: New Horizons Reveals New Godiva CollectionOver the last few years, Animal Crossing: New Horizons has seen a plethora of collaborations with [...]
Read more »
Breakthrough in Quantum Research Paves Way for New Generation of Light-Driven ElectronicsA breakthrough in quantum research – the first detection of excitons (electrically neutral quasiparticles) in a topological insulator has been achieved by an international team of scientists collaborating within the Würzburg-Dresden Cluster of Excellence ct.qmat. This discovery paves the way for a n
Read more »
The 10 best U.S. jobs of 2023, according to new research—many pay over $100,000U.S. News and World Report identified the top careers for job-seekers that offer ample job openings, strong job satisfaction and high earning potential.
Read more »
New Research Links COVID-19 Infection – and Vaccination – to a Debilitating Heart ConditionSmidt Heart Institute researchers show the risk of developing postural orthostatic tachycardia syndrome, or POTS, is five times higher after COVID-19 than after vaccination. A team of investigators from the Smidt Heart Institute at Cedars-Sinai has published research in the journal Nature Cardiov
Read more »
“Forget ‘New Year, New Me.’ Here’s to ‘New Year, Real Me.’”“This year, I don’t want to be a ‘new’ me. I want to be the old me. The authentic me. I want to shed the mask and start living fully as myself.”
Read more »
Kaley Cuoco reveals new tattoo dedicated to Tom Pelphrey at baby showerThe pregnant actress showed off some fresh ink dedicated to her partner at her “magical” baby shower over the weekend.
Read more »