Atogepant, recently approved by the FDA, prevented migraines in people who hadn't responded to other medications, according to new data.
Atogepant was developed by the company Abbvie and is sold under the brand name Qulipta. It’s part of a relatively new class of migraine drugs called calcitonin gene-related peptide inhibitors. CGRP is a protein that plays a key role in triggering and sustaining migraines and other chronic types of headache. The pill
was first approved by the FDA in 2021 to prevent episodic migraines, defined as experiencing migraines or migraine-like headaches four to 14 days a month on average.of people with episodic migraines that secured its approval, atogepant noticeably reduced the number of days with migraines compared to placebo .
The study involved around 300 people with episodic migraines who had tried at least two different classes of preventive migraine medications. About half were given 60 milligrams of atogepant a day , while the other half was given placebo. Both groups experienced a reduction in migraine days, but those on atogepant experienced about two fewer days of migraine on average compared to placebo.
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