It detects temperature changes when the virus binds to nanoparticles molecularly impressed on a 3D printed device.
Antigen tests quickly and conveniently tell a person they are positive for COVID-19, but they fail to detect early infections with low viral loads.
It is also expensive, requiring special lab equipment and trained personnel. Rapid antigen tests take 15 to 30 minutes, and untrained people can do them at home. When the team added samples from seven patient throat swabs to the device, the liquid flowed over the electrode. Unlike antibodies, the nanoMIPs withstood warm temperatures — which could give the test a longer shelf life in hot climates — and acidic pH.However, to prove that the test has a lower false-negative rate than existing rapid antigen tests, it must be tested on many more patient samples, the researchers say."However, they lack sensitivity and utilize antibodies as receptors, which can only function in narrow temperature and pH ranges.
"Therefore, nanoMIP sensors possess clear advantages over antibody-based tests as they can function in various challenging media.
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