Mutating coronavirus: What it means for all of us

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Mutating coronavirus: What it means for all of us
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Viruses such as coronavirus have a high mutation rate. What implications does it have for vaccines, treatments and testing? — via healthing_ca

, directly target the virus itself. Remdesivir specifically targets the enzyme the virus needs to replicate., but the LSHTM study didn’t find many instances of these mutations. Wide use of the drug, however, will put selective pressure on the virus , so monitoring these mutations will be important.To diagnose a current infection, diagnostic tests look for certain genes from the virus. The accuracy of these tests depends on the target areas of the genome being as expected.

Similarly, once restrictions on international travel are relaxed, scientists will need to be wary of possible false negatives among imported cases of the disease. Like mutations in any organism, for a viral mutation to prevail, it must provide an evolutionary advantage. There is no evolutionary advantage to a virus if it kills its host, particularly if it kills the host before transmitting to a new one. But evoking symptoms in the infected person, such as coughing and sneezing, can help the virus transmit to a new host and this does offer an evolutionary advantage.

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