The proportion of colon cancer diagnoses is shifting to younger people with more advanced diseases.
” tumors, suggesting that the biology of the disease could be changing, prompting a need for a new approach in prevention and more research into targeted treatments.
More patients overall are being diagnosed with regional or distant disease, which means it has spread beyond the colon to nearby or distant lymph nodes, tissues or organs. The incidence of regional stage and distant stage disease has increased by about 3 percent per year in people younger than 50, while rates have stabilized in people age 65 and older after a decade of steep decline.
The disease disproportionately affects people of color. Incidence rates are highest in Indigenous Alaskans, , Native Americans and Blacks By comparison, the incidence rate in Whites is 35.7 per 100,000. Colorectal cancer is the second most common cause of cancer death in the United States. Smoking, eating processed meats, obesity and a sedentary lifestyle are all risk factors for the disease.
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