It is high time we killed the tumors.
. Such patients had higher survival rates than those who lack the cytotoxic immune response. Based on these findings and further research work, the authors developed a DNA vaccine that could trigger cytotoxic immunity in the affected cells.Between 2001 and 2010, they conducted phase one human trials of their vaccine on 66 female patients who suffered from recurring advanced-stage HER2 cancer. Three separate groups were made during the trials.
Whereas for the second and third groups, the dosage per head was set at 100 mcg, and 500 mcg, respectively. To support and enhance the vaccine action, the researchers injected it with a soluble glycoprotein called granulocyte-macrophage colony-stimulating factor. The participants were then monitored for over a decade to check the effectiveness of the vaccine.
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