Medicare price negotiation and pharmaceutical innovation following the Inflation Reduction Act

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Medicare price negotiation and pharmaceutical innovation following the Inflation Reduction Act
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The Inflation Reduction Act (IRA) requires Medicare to negotiate lower prices for some medicines with high Medicare spending.

The Inflation Reduction Act requires Medicare to negotiate lower prices for some medicines with high Medicare spending. Using historical data from public and proprietary sources to apply the IRA’s negotiation criteria retrospectively, we identify all drugs that met the eligibility criteria from 2012 to 2021 to classify drugs that would have had a negotiated price in effect in 2022 and to calculate associated decreases in industry revenues.

Buxbaum, J., Chernew, M., Fendrick, A. & Cutler, D. Contributions of public health, pharmaceuticals, and other medical care to US life expectancy changes, 1990–2015.Google Scholar Hernandez, I., San-Juan-Rodriguez, A., Good, C. & Gellad, W. Changes in list prices, net prices, and discounts for branded drugs in the US, 2007–2018.Find and Replace: R&D Investment Following the Erosion of Existing ProductsBranstetter, L., Chatterjee, C., & Higgins, M.Abbott, T. & Vernon, J. The cost of US pharmaceutical price regulation: a financial simulation model of R&D decisions.

Dusetzina, S., Keating, N., Huskamp, H. & Mello, M. Medicare’s plan for drug-price negotiation: the importance of defining generic entry.Wouters, O., McKee, M. & Luyten, J. Estimated research and development investment needed to bring a new medicine to market, 2009–2018.R.M.C. served as an unpaid special government advisor to the Centers for Medicare and Medicaid Services in 2022 and 2023.

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