“This study is potentially going to change the way I prescribe hormones to my patients.' Long periods of hormone replacement therapy increase breast cancer risk, study says:
Described colorfully by some women as a “personal summer,” the intense waves of heat and excessive sweating that come with menopause affect millions of women each year. An estimated 12 million women in Western countries are prescribed hormone replacement therapy to combat the symptoms that happen with the decreasing levels of estrogen and progesterone associated with menopause.
“Women who use HRT for 10 years essentially double the risk of breast cancer caused by HRT than if they only use it for five years,” said Dr. Noah Kauff, an obstetrician and gynecologist and chief of Cancer Genetics at Northwell Health. He was not involved in the study. Women who take HRT can either take estrogen alone or estrogen in combination with a progestogen. For women who still have their uterus, estrogen causes excess growth of the uterine lining as an unwanted side effect, so they need to take a progestogen to balance out this effect.
“These are really individualized discussions,” she added. “Many women don’t like progestogens as it is because they can cause mood swings and bloating. I don’t want women to take less and less of their progestogens as a result of this study and then risk getting endometrial cancer.”
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