Less than a third of adult patients who were hospitalized with COVID-19 felt fully recovered one year later, with female patients and obesity among key risk factors, according to a new U.K. paper.
The study, presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases andin The Lancet Respiratory Medicine, assessed 2,320 participants across more than three dozen U.K. hospitals after five months. Among them, 807 were also assessed at the one-year mark. Patients were discharged between March 7, 2020 and April 18, 2021.
The most persistent symptoms one year after being discharged from the hospital were fatigue, aching muscles, physically slowing down, poor sleep, breathlessness, joint pain or swelling, slowing down in thinking, pain, short-term memory loss, and limb weakness, the study reported. Patients were assessed through a number of measures including patient-reported outcomes, physical performance, organ function, and blood samples.
“We showed that obesity, reduced exercise capacity, a greater number of symptoms, and increased serum C-reactive protein concentration were associated with the more severe clusters.” There are some limitations to the ongoing cohort study, the researchers said. One is the selection bias for participants returning for a one-year visit, even though no overt differences have been found between those who were assessed after a year and those who did not participate.
“Although our data are relevant to patients discharged under similar conditions, further research is needed to understand the effect of current acute care, newer SARS-CoV-2 variants, and vaccination status before and after contracting COVID-19,” researchers wrote.
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