Kyler Murray and receiver DeAndre Hopkins will both miss a second straight game when the Cardinals host the Panthers.
Murray has been bothered by an ankle injury while Hopkins has been slowed by a bum hamstring. Murray practiced some earlier this week, but coach Kliff Kingsbury said the third-year quarterback wouldn't play unless he was mobile enough to protect himself in the pocket.
Backup Colt McCoy was excellent against the 49ers, completing 22 of 26 passes for 249 yards and a touchdown. The 35-year-old will be needed again against the Panthers.
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