The treatment delivers doses of chemotherapy directly into the tumours caused by skin cancer. WorldCancerDay — via healthing_ca
, senior author of the study and a professor and vice chair of dermatology at Yale School of Medicine.
“For a lot of patients, treating skin cancer is much more involved than it would be if there was a way to effectively treat them with a simple procedure like an injection,” he said. “That’s always been a Holy Grail in dermatology — to find a simpler way to treat skin cancers such as basal cell carcinoma and squamous cell carcinoma.”
The treatment employs polymer-based nanoparticles to deliver doses of chemotherapy directly into the tumours caused by skin cancer. The nanoparticles come armed with a secret weapon — a bioadhesive property that allows them to bind directly to tumours long enough for the chemotherapy to kill off a significant number of cancer cells.
“When you inject our nanoparticles into a tumour, it turns out that they’re retained within that tumour very well,” said co-author Mark Saltzman, the Goizueta Foundation Professor of Biomedical Engineering, Chemical and Environmental Engineering, and professor of physiology. “They accumulate and bind to the tumour matrix, so one single injection lasts for a very long time — the particles stay there and slowly release the compounds. You need that to get rid of the lesion.
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