Is there an association between COVID-19 vaccination and sudden sensorineural hearing loss? medrxivpreprint COVID19 coronavirus covid vaccine vaccination hearing hearingloss
By Tarun Sai LomteJul 20 2022Reviewed by Danielle Ellis, B.Sc. In a recent study posted to the medRxiv* preprint server, researchers investigated a potential association between coronavirus disease 2019 vaccination and sudden sensorineural hearing loss .
About the study In the present study, researchers assessed the associations of COVID-19 vaccination and SARS-CoV-2 infection with SSNHL. They examined SSNHL incidence in Finland between January 1, 2019, and April 12, 2022. A national register harboring data on birth, gender, and the unique personal identification codes of all Finnish residents, was utilized to identify all people born or alive during the study.
Related StoriesThe infection status was non-infected for the entire cohort before the COVID-19 pandemic. The infected state was stratified into primary and secondary risk periods following infection. Using a Poisson regression model, the researchers computed adjusted incidence rate ratios between vaccine exposure states and the pre-epidemic non-vaccinated state and between infection exposure states and the non-infected state.
A sudden decrease in SSNHL incidence was noted in the initial phase of the pandemic that increased to pre-COVID-19 levels by the end of 2020. The crude incidence dropped shortly after the SARS-CoV-2 vaccination program commenced in early 2021. The crude SSNHL incidences during the primary risk period following first dose administration of Oxford’s ChAdOx1, BNT162b2, and Moderna’s mRNA-1273 vaccines were 24, 20.9, and 16 per 100,000, respectively.
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