Implant Automatically Releases Naloxone to Reverse Opioid Overdose

Implant Automatically Releases Naloxone To Reverse News

Implant Automatically Releases Naloxone to Reverse Opioid Overdose
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A new implant could help prevent overdose deaths by automatically administering the OD-reversing drug naloxone, a new study shows.

The implant, about the size of a stick of gum, is placed under the skin, where it monitors vital signs like

In animal studies, the device reversed potentially fatal opioid overdoses 96% of the time, according to results published Aug. 14 in the journal“Having an automated robotic system that is able to sense and reverse opiate overdose could be transformational, particularly for high-risk populations,” said senior researcher Giovanni Traverso, a clinician and biomedical engineer at MIT, Brigham and Women's Hospital and the Broad Institute..

Unfortunately, many people are alone when they overdose, and they lose consciousness before they can take their lifesaving naloxone, researchers said. Bystanders also might not recognize the symptoms of overdose or know that the person has naloxone on hand.When the device senses an overdose, it begins buzzing and sends an alert to the user's smartphone that allows them to override naloxone administration if it's a false reading, researchers said.

The implant, called “iSOS” by researchers, successfully revived 24 out of 25 overdosed pigs within a little over three minutes, researchers said.

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