A study suggests that just one night of sleep deprivation may be linked to structural changes in the brain, similar to those seen in aging.
Going just one night without sleep may make the brain look older, as if it had suddenly aged one to two years overnight, a new study suggests. In the study, researchers used machine learning to generate"brain age" estimates from magnetic resonance imaging scans of sleep-deprived people's brains, which they compared to MRIs of those same people’s brains after a full night's sleep. The results, published Feb.
The researchers determined the apparent ages of the participants' brains using a machine-learning algorithm called brainageR, which was trained on data from more than 3,000 people. The publicly available algorithm predicts a person's chronological age from their brain MRIs based on how healthy brains typically look at given ages, in terms of their tissue and fluid volume. In past tests, researchers found that brainageR could accurately predict age within about four years.
These results jibe with earlier research on the effect of sleep deprivation on the brain. There's evidence that several types of changes take place in the brains of sleep-deprived people, including changes in fluid distribution and gray matter volume.
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